The Accuris SmartSeal Semi-Automated Plate Sealer is a bench-top microplate heat sealer designed for sealing 96-well, PCR, and other microplate formats with foil, clear, pierce, or aluminum-foil seal films. The MS1000 covers the 80 °C – 200 °C temperature range (1 °C accuracy) and 0.5–10 second seal-time range (0.1 s increments) — sufficient breadth to cover essentially every microplate-sealing protocol from cold-storage strong-bonding seals to heat-sensitive PCR-plate clear seals. The semi-automated workflow combines manual plate / seal loading with motorized drawer operation (with auto-reverse safety) and automatic seal counting for workflow tracking.
Voltage options: This unit can be ordered with European voltage requirements (230V/50Hz). Contact us to order.
Key Specifications
| SKU | MS1000 |
| Voltage | AC 100–120 V, 50/60 Hz (115 V plug) |
| Display | OLED |
| Temperature setting range | 80 – 200 °C |
| Temperature accuracy | 1 °C |
| Seal time range | 0.5 – 10 s, in 0.1 s increments |
| Heating element cooling | ≤2 °C drop, returns to normal within 25 s |
| Heating element type | Electrical heating tube |
| Plate height range | 9 – 48 mm |
| Footprint width | 7.0 in (17.8 cm) — compact bench placement |
| Input power | 300 W |
| Dimensions (D × W × H) | 370 × 178 × 330 mm |
| Weight | 9.6 kg |
| Drawer mechanism | Motorized, with auto-reverse if blocked (operator-safety feature); detachable for cleaning the heating platen |
| Stand-by mode | Auto-engages after 60 min idle; heating element drops to 60 °C |
| Counter | Automatic seal counting function |
What's Included
Per the SmartSeal brochure, the MS1000 ships with the plate-sealer chassis, power cord, standard plate adapter (for standard 96-well / 384-well microplate formats), PCR plate adapter (for PCR-plate format), metal seal holder (which positions the seal film over the plate before sealing), and the operation manual.
The system is functional out-of-the-box for both standard microplate and PCR-plate workflows — no additional capital purchase required for first run. Operator-supplied: seal film consumables (MS1000-F1 / MS1000-F2 / MS1000-PCR1 / MS1000-PCR2 / MS1000-PCR3 per workflow).
Recommended Sealing Settings (per Brochure)
| Seal type | Temperature | Time |
| Most Clear-Seals | 170 °C | 2.5 s |
| Most Foil Seals | 175 °C | 3 s |
| Pierce-Seal | 180 °C | 4 s |
| Al foil-Seal | 180 °C | 4 s |
Per brochure: *"Note that sealing efficiency will vary depending on the type of plate/seal used. The above are listed as a guide. Actual temperature/time may need to be adjusted."* Recommended starting settings — actual settings should be tuned per workflow plate / seal combination.
Design Architecture
Semi-automated workflow:
- Power on — chassis begins heating to set temperature
- Set parameters — temperature (80–200 °C), seal time (0.5–10 s) via "PUSH TO SET" knob
- Load plate — press "PLATE In/Out" button to open drawer; place appropriate plate adapter in drawer; place microplate on adapter; place sealing film on plate; place weighted platen on top (recommended)
- Seal cycle — press "PLATE In/Out" to close drawer; chassis applies temperature + time + pressure; seal complete
- Unload — press "PLATE In/Out" to open drawer; remove sealed plate
Operator-safety features:
- Motorized drawer auto-reverse — if blocked during motion, drawer automatically reverses to prevent injury or damage
- 60-min idle stand-by — heating element drops to 60 °C after idle period (energy saving + reduces accidental burn risk)
- OLED display feedback — real-time temperature, time, and counter status
Plate-Format Adapter Compatibility
| Adapter | Plate format | Use case |
| Standard plate adapter (included) | Standard 96-well, 384-well, deep-well plates | Most ELISA, ELISA-development, screening, storage workflows |
| PCR plate adapter (included) | PCR plates (96-well skirted / semi-skirted / non-skirted) | qPCR plate sealing, PCR setup workflows |
| Plate height | 9 – 48 mm | Wide plate-height range covers most standard, deep-well, and PCR plate heights |
Both adapters ship included with the chassis — no additional adapter purchase required for standard workflows.
Seal-Film Consumable Pairing
The MS1000 chassis pairs with the Accuris seal-film consumable family per workflow needs:
| Seal film SKU | Seal type | Use case |
| MS1000-F1 | Foil seals, peelable, for PP plates | General-purpose peelable foil sealing |
| MS1000-F2 | Foil seals, strong bonding, cold storage (-200 to 110 °C), DMSO-compatible | Long-term cold-storage workflows; DMSO-sample storage |
| MS1000-PCR1 | Optically clear sealing film, peelable, for qPCR | qPCR plate sealing where optical clarity matters for read-through |
| MS1000-PCR2 | Pierce-seal for PCR | PCR workflows requiring needle-pierce access after sealing |
| MS1000-PCR3 | (additional PCR seal format) | Per workflow needs |
Each seal-film SKU is a separate order — confirm seal-film type and quantity at quote.
Application Profile
ELISA and immunoassay plate storage and shipping — sealed plates can be stored or shipped between facilities without sample evaporation or contamination.
Long-term sample storage in 96-well or deep-well plates — strong-bonding cold-storage seals (MS1000-F2) support -200 °C to 110 °C storage.
qPCR plate sealing — optically clear seal films (MS1000-PCR1) support qPCR runs where the seal film must transmit fluorescence excitation and emission for the qPCR reader.
DMSO-compatible sample storage — strong-bonding DMSO-compatible seals (MS1000-F2) support DMSO-sample storage (compound libraries, cell-suspension cryopreservation).
Compound library plate sealing — pharma / biotech compound library plates require strong-bonding seals for long-term storage integrity.
Multi-format research lab workflows — labs running mixed plate formats (standard 96-well + PCR + deep-well) benefit from the dual-adapter chassis design.
Frequently Asked Questions
What plate formats does the MS1000 seal? 96-well, PCR, and other microplate formats with plate heights from 9–48 mm, using foil, clear, pierce, or aluminum-foil seal films.
What is the temperature and seal-time range? 80–200 °C (1 °C accuracy) and 0.5–10 s seal time in 0.1 s increments.
What's included with the MS1000? The chassis, power cord, standard plate adapter, PCR plate adapter, metal seal holder, and operation manual. Seal-film consumables are operator-supplied.
What are the recommended sealing settings? Per brochure, most clear-seals 170 °C / 2.5 s, most foil seals 175 °C / 3 s, and pierce-seal and Al foil-seal 180 °C / 4 s — starting guides to tune per plate/seal combination.
Which seal film is used for cold or DMSO storage? The MS1000-F2 strong-bonding foil seal (-200 to 110 °C, DMSO-compatible).
Ordering & Configuration
Workflow consumable pairing. Confirm at quote: seal-film type and quantity needed for the workflow (standard peelable foil, cold-storage strong-bonding, qPCR optical clear, pierce-seal). Operator-supplied per workflow protocol.
Confirm at quote: voltage and plug type (this 115 V SKU vs the 230 V variant), workflow plate format (standard / PCR / deep-well), seal-film selection, training requirements, and lead time.
Warranty: Per Accuris standard warranty terms — confirm at quote.
Accuris SmartSeal plate-sealer family:
- MS1000 (this product) — SmartSeal Semi-Automated Plate Sealer, 115 V
- Same chassis, 230 V
- MS1000-F1 — Foil seals, peelable, 100/pk
- MS1000-F2 — Foil seals, strong bonding for cold storage / DMSO, 100/pk
- MS1000-PCR1 — Optically clear qPCR sealing film, peelable, 100/pk
Pair the chassis with the appropriate seal-film consumables per workflow protocol.
