PC-Screw Cap Lid for Z446-750-BUK (2/pk)

The Z446-750-LID is the polycarbonate (PC) screw-cap lid for the Hermle Z446-750-BUK round bucket on the Z446-750-AC 4-place swing-out rotor (Z446 / Z446-K chassis) — sold as a 2-pack. The lid engages the bucket's hermetic-seal mode for BSL-2 + biosafety workflows: when fully threaded onto the bucket, the screw cap creates an aerosol-tight envelope around the tube load. The Z446-750-AC rotor takes 4 buckets × 1 lid each = 4 lids total for full hermetic configuration — buyer needs 2 packs of this SKU. The lid is the separate purchase that activates biosafety mode on the Z446-750 rotor system; without the lid, the bucket runs in non-sealable mode.

Key Specifications

Compatibility & When to Order This SKU

This SKU activates hermetic-seal capability on the Z446-750-BUK round bucket. Order Z446-750-LID when at least one of the following applies:

1. Commissioning a Z446-750 hermetic-seal configuration — order 2 units for full 4-bucket hermetic capability (4 lids).
2. Adding biosafety capability to an existing Z446 / Z446-K + Z446-750 install that currently runs in non-sealable mode — switching the workflow into BSL-2 + biosafety requires the lid set.
3. BSL-2 + clinical workflows on the cold-chain Z446-K chassis at scale — clinical and clinical-research workflows handling potentially infectious patient samples (HIV research, hepatitis, TB, respiratory pathogens) at hospital-scale or large-cohort volume requiring both cold-chain AND biosafety containment.
4. Replacement lids if a current set is damaged, the seal interface has worn, or the lids have reached service life.
5. Spare lid inventory for facilities running mixed BSL-2 / non-BSL-2 workflows that benefit from rotating lid sets through cleaning and decontamination cycles.

Round Bucket vs Rectangular Bucket Lid Distinction

The Z446-750-AC swing-out rotor accepts two bucket profiles, each with its own lid SKU:

The lids are not interchangeable — confirm bucket geometry before ordering lids.

Why a Polycarbonate Screw Cap

The Z446-750-LID uses a PC (polycarbonate) screw-cap design consistent with the Z366-250-LID and other Hermle hermetic-seal lid families. PC screw caps offer:

• Chemical resistance — tolerates standard biosafety decontamination protocols (bleach, ethanol, peroxide-based disinfectants)
• Autoclavable — supports steam-sterilization between sample types
• Durable for repeated seal cycles — the threaded engagement maintains seal integrity over many open/close cycles
• Visually inspectable — transparent PC allows visual confirmation of the bucket interior before unsealing

The threaded screw-cap design takes longer to engage than quick-lock alternatives but provides high seal-integrity reliability for routine BSL-2 + workflows at the rotor's institutional throughput levels.

Application Profile

Cold-chain BSL-2 + clinical-blood-component prep at hospital scale — hospital and large-cohort clinical-research labs requiring both refrigeration (Z446-K at 4 °C) AND biosafety containment for routine clinical-blood prep at the highest per-cycle throughput in the Hermle catalog (Z446-750-A57 at 108 pediatric tubes/cycle, A10 at 72 × 10 mL Vacutainer/cycle).

Large clinical-research infectious-disease cohort prep — patient sample prep workflows for infectious-disease research at hospital-scale volume requiring containment from collection through cryostorage on the high-throughput cold-chain platform.

Biobank intake at institutional throughput for potentially infectious specimens — biobank prep for clinical-research studies that include BSL-2 + sample types at hospital-scale volume.

Recombinant-protein and bioprocess prep at BSL-2 on bulk-volume chassis — recombinant-protein expression workflows handling genetically modified organisms in bulk-volume bottle format with required aerosol containment.

Cross-format BSL-2 Z446-K core facilities — shared cores running mixed BSL-2 workflows across multiple tube and bottle formats benefit from the lid-engaged sealable configuration with the Z446-750-A* insert family.

Ordering & Configuration

Hermetic-seal engagement. Per Hermle service instructions, the Z446-750-LID must be fully threaded onto each bucket before each spin to maintain the hermetic envelope at 4,346 × g. Partial thread engagement does not maintain seal integrity.

Lid-bucket compatibility. The Z446-750-LID is engineered specifically for the Z446-750-BUK round bucket. Confirm bucket inventory before ordering lids; rectangular buckets (Z446-MP-BUK) require the Z446-MP-LID instead.

Z446-750-LID ships as 2 lids.

Required for operation:

• Z446-750-BUK round buckets (sold separately) — 4 buckets needed for full configuration
• Z446-750-AC rotor body (sold separately) or already in inventory
• For full 4-bucket hermetic configuration: 2 units of this LID SKU

Confirm at quote: bucket pairing (Z446-750-BUK round bucket in inventory; rectangular bucket uses Z446-MP-LID instead), chassis pairing (Z446 or Z446-K), insert family (lid is compatible with the standard Z446-750-A* insert family), lid count needed (2 packs for full 4-bucket configuration), workflow biosafety driver, and lead time.

Warranty: 5-Year Hermle warranty (3 years full + 2 years drivetrain) on the lids. The hermetic-seal interface is a planned-inspection item for biosafety workflows — Hermle's standard service interval recommendation includes the seal-integrity check.

Z446-750 hermetic-seal procurement summary:

- Z446-750-LID (this product) — 2 PC-Screw cap lids; buyer needs 2 packs (4 lids) for full 4-bucket hermetic configuration on the round bucket

- Z446-750-BUK — round buckets that the lid engages (sold separately)

- Z446-750-AC — rotor body (sold separately)

- Z446-750-A* inserts for the workflow's tube/bottle format

- Z446-MP-LID — separate lid SKU for the rectangular bucket variant (Z446-MP-BUK)

The lid is the SKU that activates BSL-2 + biosafety mode on the Z446-750 round-bucket configuration — without it, the bucket runs non-sealed.