The Z446-750-A15R is an 18-position 15 mL tube insert for the Hermle Z446-750-BUK round bucket on the Z446-750-AC 4-place swing-out rotor (Z446 / Z446-K chassis) — sold as a 2-pack. Each insert holds 18 × 15 mL tubes; the 4-bucket rotor configuration takes 2 packs (4 inserts) for full symmetric loading, delivering 72 × 15 mL tubes per cycle — among the highest 15 mL per-cycle throughput in the Hermle catalog. The Z446-750-AC's 19.2 cm max radius (largest in the Hermle swing-out family) accommodates the wide 15 mL multi-position insert geometry for institutional clinical-research and biobank workflows.
Key Specifications
| SKU | Z446-750-A15R |
| Type | Tube insert — 18 × 15 mL |
| Pack quantity | 2 inserts per SKU (full 4-bucket configuration takes 2 units = 4 inserts) |
| Per-insert capacity | 18 × 15 mL tubes |
| Per-cycle throughput (full configuration) | 72 × 15 mL tubes per cycle |
| Tube format | 15 mL (17 mm OD, 97–123 mm length range) |
| Compatible bucket | Z446-750-BUK (round bucket; with Z446-750-LID PC-Screw cap for sealable mode) |
| Compatible rotor | Z446-750-AC (4-place swing-out rotor body; or Z446-750 swing-out rotor with buckets included) |
| Compatible chassis | Z446, Z446-K (refrigerated), and -E voltage variants |
| Max. operating speed (with insert + tubes) | Per Z446-750-AC spec — 4,000/4,500 rpm at 3,434–4,346 × g maximum |
| Max. radius | 19.2 cm (with radius correction per insert spec) |
| Temperature at max speed (refrigerated chassis) | 4 °C |
| Geometry | Swing-out (0–90°) — flat sediment surface |
| List price | $572 (2-pack) |
Compatibility & When to Order This SKU
Insert pairing — Z446-750-BUK round bucket only. Order this SKU when:
- Adding institutional 15 mL workflow to an existing Z446 / Z446-K + Z446-750 install — order 2 units for full 4-bucket symmetric loading (72 tubes/cycle).
- Hospital reference labs and large clinical-research recruitment — 72 × 15 mL per cycle is sized for hospital-scale and large-cohort recruitment workflows that benefit from the highest per-cycle 15 mL throughput in the Hermle catalog.
- Cold-chain 15 mL clinical-research prep at scale — when the workflow uses the Z446-K refrigerated chassis at 4 °C max-speed temperature.
- BSL-2 + 15 mL workflows — combine with the Z446-750-LID for hermetic containment when handling potentially infectious patient samples.
- Replacement inserts if a current set is damaged or worn.
Application Profile
Among the highest 15 mL per-cycle throughput in the Hermle catalog. 72 × 15 mL tubes per cycle exceeds most other Hermle 15 mL workflows (Z366-250-B15 at 40/cycle; Z327-200-A15 at 12/cycle). The Z446-750-AC's 19.2 cm max radius accommodates the multi-position insert geometry for institutional throughput.
4-bucket symmetric loading. All 4 buckets must use matching A15R inserts for symmetric balance.
Per-insert symmetric loading. Within each insert, the 18 tubes should be balanced symmetrically — pair tubes by mass.
Optional hermetic seal via LID. When combined with the Z446-750-LID (PC-Screw cap), the bucket creates a hermetic envelope for BSL-2 + workflows.
Speed mode toggle. The Z446-750 rotor supports two speed modes (4,000 rpm / 4,500 rpm) selectable per chassis power configuration. Higher RCF (4,346 × g) requires the higher-power chassis mode.
Design Architecture
Institutional 15 mL clinical-research and biobank prep at scale — patient sample fractionation, aliquot prep, freeze-storage workflows at 72 × 15 mL per cycle on the cold-chain swing-out chassis.
Hospital reference labs at scale — clinical chemistry and hematology prep workflows handling 72 × 15 mL per cycle at institutional throughput.
Cell-culture pellet recovery in 15 mL at institutional scale — pelleting non-adherent cells from 72 parallel 15 mL suspension batches per cycle.
Density-gradient prep in 15 mL at institutional scale — Ficoll, Percoll, sucrose-gradient prep at 72 parallel preps per cycle on the cold-chain swing-out chassis.
Cold-chain protein prep in 15 mL at scale — TCA, ammonium-sulfate, organic-precipitation in 15 mL working volume at 72 parallel preps with refrigeration.
BSL-2 + 15 mL clinical workflows — patient samples in 15 mL format requiring aerosol containment via the Z446-750-LID.
Cross-format Z446-K core facilities — labs running 15 mL workflow at scale alongside other Z446-750 insert formats benefit from the cross-format insert family.
Ordering & Configuration
4-bucket symmetric loading. All 4 buckets must use matching A15R inserts. Mixed-bucket configurations produce mass asymmetry.
Optional hermetic-seal engagement. When using the Z446-750-LID for biosafety workflows, confirm the lid is fully threaded onto each bucket before each spin.
Tube cap confirmation. All 15 mL tubes must be securely capped before spinning at 4,500 rpm.
Z446-750-A15R ships as 2 inserts. 15 mL tubes are operator-supplied (commodity 15 mL conical or round-bottom formats from major commercial suppliers). The Z446-750-BUK bucket and (optional) Z446-750-LID are sold separately.
Confirm at quote: bucket pairing (Z446-750-BUK in inventory; Z446-750-LID if biosafety required), chassis pairing (Z446 or Z446-K) and power configuration (affects max speed mode), tube format (15 mL), pack count (2 packs for full 4-bucket configuration), and lead time.
Warranty: 5-Year Hermle warranty (3 years full + 2 years drivetrain) on the inserts.
Z446-750 high-throughput insert family (Z446-750-AC swing-out rotor):
- Z446-750-A15R (this product) — 18 × 15 mL (72/cycle, among highest in catalog)
- Z446-750-A10 — 18 × 6–10 mL Vacutainer (72/cycle)
- Z446-750-A57 — 27 × 1.8–7 mL pediatric / small-volume blood tubes (108/cycle)
- Z446-750-A50R — 7 × 50 mL round (28/cycle)
Match the insert to the workflow's tube format. The Z446-750 platform delivers the highest per-cycle clinical-research throughput in the Hermle catalog at 19.2 cm max radius.
