The Z446-750-A57 is a 27-position 1.8–7 mL Vacutainer-style pediatric blood tube insert for the Hermle Z446-750-BUK round bucket on the Z446-750-AC 4-place swing-out rotor (Z446 / Z446-K chassis) — sold as a 2-pack. Each insert holds 27 × pediatric / small-volume Vacutainer tubes; the 4-bucket rotor configuration takes 2 packs (4 inserts) for full symmetric loading, delivering 108 × 1.8–7 mL Vacutainer tubes per cycle — the highest per-cycle clinical-blood-tube throughput in the entire Hermle catalog. The Z446-750-AC's 19.2 cm max radius (largest in the Hermle swing-out family) accommodates the 27-position multi-tube insert geometry.
Key Specifications
| SKU | Z446-750-A57 |
| Type | Tube insert — 27 × 1.8–7 mL Vacutainer-style |
| Pack quantity | 2 inserts per SKU (full 4-bucket configuration takes 2 units = 4 inserts) |
| Per-insert capacity | 27 × 1.8–7 mL Vacutainer-style tubes |
| Per-cycle throughput (full configuration) | 108 × 1.8–7 mL Vacutainer tubes per cycle (highest in Hermle catalog) |
| Tube format | 1.8 mL, 5 mL, or 7 mL clinical Vacutainer-style (~13 mm OD, 75–100 mm length) |
| Compatible bucket | Z446-750-BUK (round bucket; with Z446-750-LID PC-Screw cap for sealable mode) |
| Compatible rotor | Z446-750-AC (4-place swing-out rotor body) |
| Compatible chassis | Z446, Z446-K (refrigerated), and -E voltage variants |
| Max. operating speed (with insert + tubes) | Per Z446-750-AC spec — 4,000/4,500 rpm at 3,434–4,346 × g maximum |
| Max. radius | 19.2 cm |
| Temperature at max speed (refrigerated chassis) | 4 °C |
| Geometry | Swing-out (0–90°) — flat sediment surface |
| List price | $489 (2-pack) |
Compatibility & When to Order This SKU
Insert pairing — Z446-750-BUK round bucket only. Order this SKU when:
- Adding pediatric / small-volume clinical-blood-tube workflow at maximum throughput — order 2 units for full 4-bucket symmetric loading (108 tubes/cycle).
- Hospital pediatric reference labs at scale — 108 × pediatric Vacutainer per cycle is sized for hospital-scale pediatric clinical-blood-component prep where institutional volume justifies the highest throughput in the catalog.
- Large pediatric clinical-research cohorts — recruiting-phase studies that draw pediatric / small-volume tubes at high per-day volume.
- Cold-chain pediatric clinical workflows at scale — when the workflow uses the Z446-K refrigerated chassis at 4 °C max-speed temperature.
- BSL-2 + pediatric clinical workflows — combine with the Z446-750-LID for hermetic containment when handling potentially infectious pediatric samples.
- Replacement inserts if a current set is damaged or worn.
Highest Per-Cycle Clinical-Blood-Tube Throughput in the Hermle Catalog
The 108-tube-per-cycle throughput exceeds all other Hermle clinical-blood-tube configurations:
| Rotor + insert | Per cycle |
| Z446-750-A57 (this SKU) | 108 × 1.8–7 mL Vacutainer |
| Z366-250-A57 / B57 | 56 × 1.8–7 mL Vacutainer |
| Z327-200-A57 | 32 × 1.8–7 mL Vacutainer |
| Z326-100H-A57 | 16 × 5/7 mL Vacutainer |
The Z446-750 platform's 19.2 cm max radius (largest in the swing-out family) plus the 27-position-per-insert density delivers institutional-throughput pediatric clinical-blood-component prep on a single chassis — the right pick when hospital-scale or large-cohort recruitment workflow drives the throughput requirement.
Application Profile
4-bucket symmetric loading. All 4 buckets must use matching A57 inserts for symmetric balance.
Per-insert symmetric loading. Within each insert, the 27 tubes should be balanced symmetrically. Mixed 1.8/5/7 mL runs require pre-balance by total tube + sample mass.
Optional hermetic seal via LID. When combined with the Z446-750-LID, the bucket creates a hermetic envelope for BSL-2 + small-volume blood-tube workflows.
Speed mode toggle. The Z446-750 rotor supports two speed modes (4,000 rpm / 4,500 rpm) selectable per chassis power configuration.
Design Architecture
Hospital pediatric clinical-blood-component prep at maximum scale — hospital pediatric labs and pediatric reference labs that batch institutional volume of pediatric samples per cycle for serum/plasma separation (108 patient samples per cycle).
Large pediatric infectious-disease cohort prep — pediatric infectious-disease research (pediatric HIV, pediatric TB, pediatric respiratory pathogen studies) at large-cohort scale where the highest per-cycle throughput is the workflow driver.
Cold-chain large-cohort clinical-research recruitment — recruiting-phase studies that draw 5 mL or 7 mL collection tubes at hospital-scale per-day volume on the cold-chain biosafety chassis.
Veterinary clinical at institutional scale — institutional veterinary practice or veterinary-research lab throughput in 5/7 mL Vacutainer-style format.
Hospital reference labs handling large pediatric specimen volume — pediatric clinical chemistry and hematology prep at the highest available institutional throughput on the Z446-K platform.
Cross-format Z446-K core facilities — labs running pediatric tubes at scale alongside other Z446-750 insert formats benefit from the cross-format insert family on a single chassis with the highest swing-out throughput in the catalog.
Ordering & Configuration
4-bucket symmetric loading. All 4 buckets must use matching A57 inserts. Mixed-bucket configurations produce mass asymmetry.
Per-insert symmetric loading. Within each insert, the 27 tubes should be balanced symmetrically. Pre-balance by total mass for mixed-volume runs.
Tube cap confirmation. All Vacutainer rubber stoppers must be fully seated before spinning at 4,500 rpm.
Optional hermetic-seal engagement. When using the Z446-750-LID for biosafety workflows, confirm the lid is fully threaded onto each bucket before each spin.
Z446-750-A57 ships as 2 inserts. 1.8/5/7 mL Vacutainer-style tubes are operator-supplied (commodity clinical phlebotomy supplies). The Z446-750-BUK bucket and (optional) Z446-750-LID are sold separately.
Confirm at quote: bucket pairing (Z446-750-BUK in inventory; Z446-750-LID if biosafety required), chassis pairing (Z446 or Z446-K) and power configuration (affects max speed mode), tube format (1.8/5/7 mL Vacutainer-style), workflow drivers (cold-chain, biosafety, hospital-scale pediatric throughput), pack count (2 packs for full 4-bucket configuration), and lead time.
Warranty: 5-Year Hermle warranty (3 years full + 2 years drivetrain) on the inserts.
Hermle pediatric / small-volume Vacutainer rotor selection by per-cycle throughput:
- Z446-750-A57 (this product) — 108/cycle on Z446-750-AC (highest in catalog)
- Z366-250-A57 / B57 — 56/cycle on Z366 chassis
- Z327-200-A57 — 32/cycle on Z327 chassis
- Z326-100H-A57 — 16/cycle on Z327 chassis (sealed bucket variant)
Pick the Z446-750-A57 when the workflow needs hospital-scale pediatric clinical-blood-component prep throughput; pick smaller-throughput configurations on lighter chassis when institutional volume isn't the workflow driver.
