The Yamato ONC-362DS001GR is the On-chip Droplet Selector HSGR, a microfluidic instrument that identifies, sorts, and dispenses specific water-in-oil (W/O) droplets containing cells or microorganisms. It enables high-throughput, damage-free screening of encapsulated samples and dispenses individual selected droplets directly into 96- or 384-well plates, one droplet at a time. This HSGR configuration is equipped with 488 nm, 638 nm, and 561 nm excitation lasers — a three-line set spanning blue, far-red, and orange/yellow-green for broad multiparameter panels.
Key Specifications
| SKU | ONC-362DS001GR |
| Product | On-chip Droplet Selector HSGR |
| Detection lasers | 488 nm, 638 nm, 561 nm |
| Sample format | Water-in-oil (W/O) droplets encapsulating cells or microorganisms |
| Function | Identify, sort, and dispense selected droplets |
| Dispensing | Direct into 96- or 384-well plates, one droplet at a time |
| Handling | High-throughput, damage-free (gentle) screening |
| List price | Contact for pricing (TBA) |
Application Profile
Each water-in-oil droplet in a microfluidic screen is a sealed picoliter reactor — one cell and its assay, isolated from every neighbor — which makes droplet sorting a backbone technology for single-cell and single-microorganism screening. The challenge is pulling the *right* droplet out intact. The On-chip Droplet Selector reads each droplet's fluorescence in real time, matches it against the target gate, and dispenses only the winners into a defined well, leaving their contents unharmed.
Because dispensing is damage-free, selected cells or microorganisms reach the destination well viable and ready for clonal expansion, sequencing, or culture. Placing one droplet at a time into addressable 96- or 384-well plates supports single-cell isolation, antibody discovery, directed evolution, and rare-variant enrichment. The HSGR laser combination (488/638/561 nm) is the choice when a panel needs both far-red (638 nm) *and* 561 nm-excited reporters simultaneously — the broadest of the three variants for multiplexed gating.
Frequently Asked Questions
What does the On-chip Droplet Selector do? It identifies, sorts, and dispenses specific water-in-oil (W/O) droplets containing cells or microorganisms, placing selected droplets directly into well plates.
Which lasers does this HSGR model have? The HSGR (ONC-362DS001GR) is equipped with 488 nm, 638 nm, and 561 nm excitation lasers.
When should I pick the HSGR configuration? Choose HSGR when your assay needs both the far-red 638 nm line and the 561 nm line together — the widest multiparameter coverage among the three variants.
Where are the sorted droplets dispensed? Directly into 96- or 384-well plates, one droplet at a time, so each well receives a defined, selected droplet.
Is the sorting gentle on cells? Yes — damage-free dispensing keeps encapsulated cells or microorganisms intact for downstream culture, sequencing, or analysis.
How do the HS, HSG, and HSGR versions differ? Only by their laser configuration. HSGR uses 488/638/561 nm; HS (ONC-362DS001) uses 488/638/405 nm; HSG (ONC-362DS001G) uses 488/561/405 nm.
Ordering & Configuration
Confirm at quote: your fluorophore panel (to select HS vs HSG vs HSGR), target plate format (96 vs 384), and chip/consumable supply.
Warranty: Per Yamato standard capital-equipment terms — confirm coverage at quote.
Add to a quote to request current pricing and lock configuration and lead time.
On-chip Droplet Selector variants (laser set is the only difference):
- HSGR — ONC-362DS001GR (this product) — 488 / 638 / 561 nm
- HS — ONC-362DS001 — 488 / 638 / 405 nm
- HSG — ONC-362DS001G — 488 / 561 / 405 nm
Pick the variant whose excitation lines match your reporters; the sorting, dispensing, and damage-free handling are identical across all three.
