The AP1024-TC is the 24-place magnetic tip comb consumable for the Accuris AP1024 IsoPure 24 Automated Purification System — sold as pack of 25 combs per the 2026 universe price-list. The tip comb is the per-cycle consumable that holds the magnetic-bead transfer tips for the IsoPure 24's automated bead-transfer workflow across the 24-sample plate format. One tip comb is consumed per extraction cycle, alongside one AP1024-DWP deep-well plate.
Pack-size discrepancy note (linked to FQ-013): The AP1024 brochure ordering table specifies *"Tip Comb for IsoPure 24, pack of 50"* — but the 2026 universe price-list label specifies pack of 25. This is the same brochure-vs-universe pack-size discrepancy pattern as AP1024-DWP (24/pack universe vs 50/pack brochure). FQ-013 in fred_followup_queue.md queues both AP1024 consumable pack-quantity questions to Accuris. Page is authored to the universe spec (25/pack).
Key Specifications
| SKU | AP1024-TC |
| Type | 24-place magnetic tip comb for IsoPure 24 magnetic-bead transfer |
| Pack quantity | 25 combs per pack (per 2026 universe price-list — see discrepancy note) |
| Tip count per comb | 24 (one tip per sample, supporting up to 24 samples per cycle) |
| Compatible chassis | AP1024 IsoPure 24 |
| Compatible plate | AP1024-DWP 14.6 mL deep-well plate |
| Magnetic assembly | Pairs with chassis 24-place magnetic assembly per brochure |
| Workflow scale | 1–24 samples per IsoPure 24 cycle |
| List price | $230 (pack of 25) |
Compatibility & When to Order This SKU
Tip comb consumable — IsoPure 24 chassis only. Order this SKU when:
- Initial chassis commissioning — order an initial supply when commissioning a new AP1024 chassis to support workflow startup.
- Workflow-recurring replenishment — every IsoPure 24 extraction cycle consumes one tip comb; pack-quantity replenishment cadence depends on workflow throughput.
- High-throughput facility consumable inventory — labs running daily IsoPure 24 batches consume tip combs at a steady cadence; centralized inventory supports continuous operation.
- Multi-chassis facilities — facilities running multiple IsoPure 24 chassis maintain consolidated tip-comb stock to avoid per-chassis ordering overhead.
IsoPure 24 Per-Cycle Consumable Trio
Per the AP1024 brochure, every IsoPure 24 extraction cycle requires three workflow-mandatory items:
| Item | SKU | Per-cycle quantity |
| Tip comb (this SKU) | AP1024-TC | 1 |
| Deep-well plate | AP1024-DWP | 1 |
| Magnetic assembly | (chassis-included) | (chassis-resident, not per-cycle consumable) |
The 24-place magnetic assembly is chassis-resident (built into the IsoPure 24 chassis); the tip comb and deep-well plate are the per-cycle consumables. Confirm both consumable inventories at order — running out of either stalls the workflow.
Design Architecture
Bead-transfer mechanism. The IsoPure 24's magnetic comb assembly engages the AP1024-TC tip comb at the start of each protocol step, moves through the deep-well plate's wells in protocol-step sequence (lysis → binding → wash 1 → wash 2 → wash 3 → elution), and uses magnetization / demagnetization cycles to transfer the magnetic beads through the wells.
One comb per cycle, no reuse. The tip comb is discarded at the end of each cycle to prevent cross-cycle contamination — standard magnetic-bead purification consumable practice.
Sterile / contaminant-free packaging. Per Accuris consumable conventions, the tip combs are sterile-packed and contaminant-free for nucleic-acid extraction workflows. Confirm batch lot sterility certificate at order if the workflow requires documented chain-of-custody for sterility.
Application Profile
Per-cycle workflow consumable for all IsoPure 24 extractions — DNA / RNA / protein magnetic-bead extraction workflows on the IsoPure 24 chassis.
High-throughput nucleic-acid extraction — sequencing core facilities, biotech R&D groups, and clinical-research labs running 24-sample batch extractions.
Method-development workflows — protocol-validation runs on the IsoPure 24 chassis consume tip combs; include in validation-experiment budget.
Multi-chassis facility consumable management — consolidated purchasing for shared facilities running multiple IsoPure 24 chassis.
Ordering & Configuration
Per-cycle workflow consumable. Each IsoPure 24 extraction cycle uses one tip comb. Plan procurement to match the workflow's per-month or per-quarter cycle count.
Pair with AP1024-DWP deep-well plate. Both consumables are required per cycle; confirm both inventories at order.
Confirm at quote: chassis pairing (AP1024 in inventory), workflow throughput, pack-quantity confirmation (25 vs 50 per FQ-013 query), deep-well plate inventory (AP1024-DWP), and lead time.
Warranty: Per Accuris standard consumable terms — confirm at quote.
Accuris IsoPure 24 per-cycle consumable family:
- AP1024-TC (this product) — 24-place tip comb, 25/pack
- AP1024-DWP — 14.6 mL deep-well plate, 24/pack
Both consumables are required per IsoPure 24 extraction cycle.
