The AP1016-MC is the 8-place magnetic tip comb consumable for the Accuris AP1016 IsoPure Mini Automated Purification System — sold as case of 50 combs. The magnetic tip comb is the per-cycle consumable that holds the magnetic-bead transfer tips for the IsoPure Mini's automated bead-transfer workflow. Per the IsoPure Mini brochure: *"The 8-place magnetic tip combs lock into position inside the instrument's processing chamber."* The combs are sterile-packed and guaranteed contaminant-free per the brochure's consumable-quality language.
Key Specifications
| SKU | AP1016-MC |
| Type | 8-place magnetic tip combs for magnetic-bead transfer |
| Pack quantity | Case of 50 combs |
| Compatible chassis | AP1016 IsoPure Mini |
| Tip count per comb | 8 (one tip per sample, supporting up to 8 samples per cycle on the 6-well strip workflow) |
| Loading mechanism | Locks into position inside the IsoPure Mini's processing chamber per brochure |
| Sterility | Sterile-packed, contaminant-free per Accuris brochure |
| List price | $73 (case of 50) |
Compatibility & When to Order This SKU
Tip comb consumable — IsoPure Mini chassis only. Order this SKU when:
- Initial chassis commissioning — order an initial supply of tip combs (case of 50 minimum) when commissioning a new AP1016 chassis to support workflow startup.
- Workflow-recurring replenishment — magnetic-bead purification consumes one tip comb per protocol run; replenishment cadence depends on workflow throughput. A case of 50 supports 50 extraction cycles before reorder.
- Spare-inventory for multi-chassis facilities — facilities running multiple IsoPure Mini chassis benefit from spare tip-comb cases on hand to avoid workflow stalls.
- Production-throughput labs — labs running daily extraction batches consume tip combs at ~5 cases / month or more depending on batch size.
Magnetic Tip Comb Architecture
The IsoPure Mini's automated workflow uses a magnetic comb mechanism to transfer beads between protocol-step wells (lysis → binding → wash 1 → wash 2 → wash 3 → elution). The mechanism:
- Engages the tip comb — the comb locks into position inside the processing chamber per brochure
- Moves between wells — the magnetic comb assembly moves the tips through the sample-vessel wells in protocol-step sequence
- Captures beads via magnet — at each magnetization step, the tips collect the magnetic beads from the well
- Transfers beads to the next well — the comb moves to the next protocol-step well and releases beads via demagnetization
One comb per cycle — the comb is consumed (discarded) at the end of each cycle to prevent cross-cycle contamination. The 8-place format matches the 8-tip workflow for 1–8 sample 6-well-strip extractions.
Sterile / contaminant-free packaging. Per brochure: the consumables are *"manufactured and packaged in a sterile environment"* and *"guaranteed to be contaminant-free."* This sterility supports nucleic-acid extraction workflows where DNase / RNase contamination would compromise sample integrity.
Application Profile
DNA / RNA / protein extraction on IsoPure Mini — every IsoPure Mini extraction cycle requires one tip comb. The tip comb is workflow-mandatory, not optional.
Production-throughput consumable inventory — labs running daily IsoPure Mini extractions size their tip-comb inventory to support continuous operation without restocking gaps.
Multi-chassis facility consumable management — shared facilities running multiple IsoPure Mini chassis maintain centralized tip-comb inventory.
Method-development and protocol-validation runs — every validation run consumes a tip comb; method-development workflows include tip-comb procurement in the validation-experiment budget.
Ordering & Configuration
Per-cycle workflow consumable. Each IsoPure Mini extraction cycle uses one tip comb. Plan procurement to match the workflow's per-month or per-quarter cycle count.
Pair with sample-vessel consumable. The tip comb pairs with either the 6-well sample strip + aluminum rack workflow (1–8 samples) or the 96 deep-well plate workflow (9–16 samples). The tip comb itself is format-independent within the IsoPure Mini chassis.
Confirm at quote: chassis pairing (AP1016 in inventory), workflow throughput (per-month extraction cycle count drives case quantity), and lead time.
Warranty: Per Accuris standard consumable terms — confirm at quote. Sterility / contaminant-free guarantee per brochure.
Accuris IsoPure Mini per-cycle consumable family:
- AP1016-MC (this product) — 8-place magnetic tip combs, case of 50 (per-cycle consumable, format-independent)
- AP1016-6W — 6-well sample strips, case of 100 (low-throughput sample-vessel consumable)
- AP1016-ASR — Aluminum Sample Rack (durable adapter for 6-well strips)
Tip combs are mandatory per cycle; size case quantity to workflow throughput.
