The MR9620 SmartReader™ MultiMode is the three-mode flagship of the Accuris microplate-reader line — a single instrument that performs absorbance, fluorescence, and luminescence assays on 6-well through 384-well plates, with a built-in incubator (RT +4 °C to 45 °C), programmable shaking (linear at 4.7 / 7.0 / 13.5 Hz, orbital, and double-orbital from 240 to 1,200 rpm), and a 10-inch touchscreen for direct on-instrument operation. This is the spec for cores that consolidate ELISA, kinetic enzyme assays, fluorometric DNA / protein quantitation, and reporter-gene luminescence into one instrument rather than maintaining separate dedicated readers per mode. Catalog note: MR9620 lives under "Accuris MR9610/MR9611 Accessories" in the 2026 price list section header — the catalog placement is a sales artifact; this is a $26,344 standalone flagship, not an accessory.
Voltage options: This unit can be ordered with European voltage requirements (230V/50Hz). Contact us to order.
Key Specifications
General
| Measurement modes | Absorbance, Fluorescence, Luminescence |
| Plate formats | 6-well through 384-well |
| Shaking | Linear (4.7 Hz, 7.0 Hz, 13.5 Hz); orbital; double-orbital (240–1,200 rpm) |
| Incubation range | Room temperature +4 °C to 45 °C |
| Temperature uniformity | ± 0.5 °C @ 37 °C |
| Display | 10.0-inch touchscreen |
| Communication ports | 2 × USB-A, 1 × USB-B, 1 × Ethernet, RS232 |
| Dimensions (W × D × H) | 42.0 × 55.0 × 38.6 cm (16.5 × 21.7 × 15.2 in) |
| Weight | 33 kg (72.8 lb) |
| Power input | AC 100–240 V universal, 50–60 Hz |
| List price | $26,344 |
Absorbance mode
| Light source | High-energy xenon flash lamp |
| Detector | Photodiode |
| Wavelength range | 200 – 1,000 nm in 1 nm steps |
| Wavelength accuracy | ± 2 nm |
| Wavelength repeatability | 0.2 nm |
| Bandwidth (FWHM) | > 2.5 nm |
| Absorbance range | 0.0 – 4.0 OD |
| Resolution | 0.0001 OD |
| Accuracy (96-precision mode) | ± (1.0 % + 0.003 Abs) at 0.0–2.0 Abs; ± 2.0 % at 2.0–3.0 Abs |
| Repeatability | CV < 1.0 % or SD < 0.003 (Fast); CV < 0.5 % or SD < 0.003 (Accurate); both at 0.0–3.0 Abs |
| Stray light | 0.1 % at 220 nm |
| Linearity | R² > 0.999 at 0.0–3.0 Abs |
| Measurement speed | < 15 seconds per plate |
Fluorescence mode
| Reading mode | Top reading |
| Excitation source | High-energy xenon flash lamp |
| Detector | Photo Multiplier Tube (PMT) |
| Detection limit | ≤ 1 pM |
| Excitation range | 200 – 1,000 nm |
| Emission range | 270 – 850 nm |
| Included filter cartridges (EX / EM) | 470 / 525 nm; 523 / 564 nm; 624 / 692 nm |
| Linear dynamic range | 6 logs |
Luminescence mode
| Detector | Photo Multiplier Tube (PMT) |
| Detection limit | 15 amol / well |
| Linear dynamic range | 6 logs |
| Crosstalk | ≤ 0.005 % |
Application Profile
ELISA and absorbance-based immunoassays. 200–1,000 nm wavelength range covers the standard ELISA chromogenic substrates (TMB at 450 nm, OPD at 492 nm, ABTS at 405 nm) plus protein assays (BCA at 562 nm, Bradford at 595 nm, Lowry at 750 nm) and nucleic-acid quantitation (260 / 280 nm in microvolume mode with the SmartDrop accessory plate).
Fluorescence quantitation of nucleic acids and proteins. Three included filter cartridges cover the most common fluorometric assays: PicoGreen / SYBR-class DNA assays at 470/525 nm, Hoechst-class DNA at 350/450 nm range (with optional cartridge), Texas Red and rhodamine derivatives at 523/564 nm, and far-red DNA dyes / Cy5 at 624/692 nm. Detection limit ≤ 1 pM puts the MR9620 in the same sensitivity class as dedicated fluorometers for routine quantitation work.
Reporter-gene luminescence. Firefly and Renilla luciferase reporter assays (cell-based gene-expression studies, dual-luciferase reporter workflows) use the luminescence mode at 15 amol/well detection limit and < 0.005 % crosstalk between adjacent wells — important for kinetic and high-density plate workflows.
Kinetic enzyme assays at controlled temperature. Built-in incubator from RT +4 °C to 45 °C with ± 0.5 °C uniformity at 37 °C supports kinetic absorbance and fluorescence reads (Michaelis-Menten kinetics, enzyme inhibitor screens) without a separate incubator-shaker pre-step.
Cell-based assays with shaking. Three linear-shake frequencies plus orbital and double-orbital shaking (240–1,200 rpm) cover the full range of cell-suspension homogenization and reagent-mixing protocols required for cell-based assays.
Drug-discovery primary screening. 384-well plate format support plus the multi-mode capability lets a single MR9620 cover hit-discovery (luminescence reporter), confirmation (fluorescence binding assay), and counter-screening (absorbance cell-viability) in one instrument.
Design Architecture
High-energy xenon flash lamp as the universal excitation source for both absorbance and fluorescence — single-source design eliminates lamp-warm-up drift between modes and provides consistent intensity across the 200–1,000 nm range. Flash-lamp lifespan is significantly longer than continuous xenon arc sources at equivalent intensity.
Photodiode (absorbance) + PMT (fluorescence and luminescence) detector pairing. The photodiode is optimal for absorbance — wide dynamic range, fast response, low noise across the visible / near-UV spectrum. The PMT is essential for the photon-counting sensitivity required by fluorescence (≤ 1 pM) and luminescence (15 amol/well) — single-photon detection class, which a photodiode cannot achieve.
10-inch touchscreen for on-instrument operation. The MR9620 doesn't require a tethered PC for routine operation — protocols are programmed and reads are launched directly on the touchscreen. PC connection (USB-B and Ethernet) is for data export and the optional SmartReader PC software (MR9620-PC) when centralized data management or 21 CFR Part 11 audit trails (MR9620-CFR) are required.
Built-in incubation with ± 0.5 °C uniformity. Most multi-mode readers in this price class require a separate incubator-shaker pre-step for temperature-sensitive assays. The MR9620's integrated incubation removes the sample-transfer step and the temperature drift it introduces.
Three shaking modes (linear / orbital / double-orbital) at three programmable frequencies. Linear at 4.7 / 7.0 / 13.5 Hz covers reagent-mixing and cell-suspension homogenization. Orbital and double-orbital at 240–1,200 rpm cover cell-based assay shaking and bead-suspension resuspension. The shaker is integrated with the read scheduler so the operator can program shake-then-read protocols without manual intervention.
Optional Automatic Injection Modules (AIM1, AIM2) — sold separately. For fast-kinetics workflows (Ca²⁺ flux, BRET / FRET kinetics, luminescence flash assays) where reagent must be injected immediately before the read, the MR9620-AIM1 (single injector) and MR9620-AIM2 (dual injector) accessories add inline injection capability.
SmartDrop accessory plate (MR9610-SDP, sold separately) — converts the MR9620 into a microvolume nucleic-acid quantitation reader, eliminating the need for a separate NanoDrop-class instrument when nucleic-acid quant is occasional rather than primary workflow.
FDA 21 CFR Part 11 software option (MR9620-CFR, sold separately) — for regulated-environment use, the 21 CFR Part 11 PC software adds audit-trail logging, electronic signatures, and data-integrity controls required by FDA-regulated and GLP-regulated facilities.
Frequently Asked Questions
What measurement modes does the MR9620 support? Three: absorbance, fluorescence, and luminescence — all in one instrument on 6-well through 384-well plates.
Does the MR9620 have a built-in incubator? Yes. It incubates from room temperature +4 °C to 45 °C, with ± 0.5 °C uniformity at 37 °C, and supports linear, orbital, and double-orbital shaking from 240 to 1,200 rpm.
How does the MR9620 differ from the MR9610 and MR9611? The MR9610 (absorbance-only, $26,344.00) and MR9611 (absorbance plus cuvette port, $26,344.00) cover single-mode workflows. The MR9620 earns its premium when the lab needs all three detection modes, or when fluorescence sensitivity (≤ 1 pM) is workflow-critical.
Can the MR9620 add reagent injection for fast-kinetics assays? Yes, via the optional MR9620-AIM1 (single injector) or MR9620-AIM2 (dual injector) modules, sold separately.
Is there a 21 CFR Part 11 option? Yes — the MR9620-CFR PC software adds audit-trail logging and electronic signatures for FDA/GLP-regulated environments.
Ordering & Configuration
Standard configuration. The MR9620 ships with the instrument, three pre-installed filter cartridges (470/525, 523/564, 624/692 nm), 115 V power cord, operator's manual, and packaging materials (retain for service shipments). Cardboard / foam packaging is required for return-to-service shipping per the brochure — keep it.
Voltage variants:
- MR9620 — 115 V plug (this SKU)
Compatible accessories:
- MR9620-AIM1 — Automatic Injection Module, set of 1 (single injector for fast-kinetics workflows)
- MR9620-AIM2 — Automatic Injection Module, set of 2 (dual injector)
- MR9610-SDP — SmartDrop Accessory Plate (converts the reader to microvolume nucleic-acid quantitation; shared with MR9610 / MR9611 readers)
- MR9620-PC — SmartReader Multimode PC Software (Research Version)
- MR9620-CFR — SmartReader Multimode PC Security Software (FDA 21 CFR Part 11 compliant)
This is institutional capital procurement at $26K. Use the quote request to confirm: voltage and plug type for installation, whether AIM1 / AIM2 injection modules are part of the workflow, whether SmartDrop microvolume capability is needed (drives MR9610-SDP inclusion), whether 21 CFR Part 11 audit-trail software is required (MR9620-CFR), training and on-site validation services, and lead time. Pre-installation site survey typical when filter cartridges beyond the included three are part of the workflow specification.
Warranty: Manufacturer's standard Accuris warranty applies. Service, calibration validation, lamp replacement, and filter-cartridge expansion are available through the Accuris service network (Accuris Instruments is a division of Benchmark Scientific).
Mode-comparison note for buyers: if the workflow is absorbance-only (ELISA, protein assays, microplate-format spectroscopy), the MR9610 (UV-Vis) at $26,344.00 covers it without paying for the fluorescence and luminescence modes. If absorbance + microvolume nucleic-acid is the primary workflow, the MR9611 (UV-Vis with Cuvette Port) at $26,344.00 adds cuvette-format quantitation. The MR9620 earns its premium when the lab needs all three detection modes in a single instrument, or when fluorescence sensitivity (≤ 1 pM detection limit) is workflow-critical.
