The Z600-S3-TC is the temperature-controlled variant of Hermle's SIEVA-3 filtration centrifuge. The base SIEVA-3 separates solid-from-liquid by spinning a perforated basket lined with a defined-pore filter — driving the liquid phase through and retaining solids inside the basket. The TC variant adds a connection for an external temperature-equalization circulator to the chamber jacket, allowing the operator to drive chilled or heated fluid through the chassis during separation. This is the spec for thermolabile crystallizates, temperature-dependent separation kinetics, and any filtration workflow where ambient temperature would degrade the separated product.
Voltage options: This unit can be ordered with European voltage requirements (230V/50Hz). Contact us to order.
Key Specifications
| Max. speed | 10,000 rpm |
| Max. RCF | 7,825 × g |
| Acceleration | 9 sec |
| Deceleration | 12 sec |
| Basket capacity | 500 mL (perforated or non-perforated) |
| Filter material | PP DWL, pore sizes 7 µ / 20 µ / 30 µ / 50 µ |
| Speed pre-selection | 200 – 10,000 rpm in 10-rpm increments |
| Running time | 10 sec to 99 h 59 min, or continuous |
| Power input | 0.85 kW |
| Power supply | 120 V / 50–60 Hz |
| External temperature control | Connection for circulator (chilled or heated fluid loop, customer-supplied) |
| Dimensions (W × H × D) | 38 × 32 × 50 cm |
| Weight | ~37 kg (V01/V02) or ~43 kg (V03/V04/V05) |
| Compliance | CE, IEC 61010, IEC 61010-2 |
Application Profile
Thermolabile crystallizate isolation. Pharmaceutical intermediates and APIs whose crystal structure or stability depends on temperature need the separation step to occur at the same temperature as the upstream synthesis or formulation step. The TC chassis maintains chamber temperature via the external fluid loop.
Cold-chain biotechnology workflows. Enzyme-stabilized fermentation broths, cold-stored intermediates, and cryoprotected suspensions where ambient warming during a 20-minute filtration cycle would cause degradation or aggregation.
Temperature-dependent separation kinetics. Some particulate-suspension separations (certain polymorphic forms, pharmaceutical hydrates, biological matrix workflows) shift cake characteristics with temperature — the TC chassis lets the operator hold separation temperature constant rather than letting it drift through the cycle.
Hot-filtration workflows. Less common but supported — drive heated fluid through the jacket to maintain a hot mother liquor at separation temperature, preventing premature crystallization in the basket during filtration of supersaturated solutions.
Pharmaceutical scale-up validation. Method-development work that needs to characterize separation behavior across a temperature range benefits from the controlled-temperature chassis.
Design Architecture
External temperature-equalization connection. The TC variant adds a fluid-loop connection (inlet + return) on the chassis for a customer-supplied recirculating heater / chiller. Hermle does not bundle the circulator — operators size and source the circulator per workflow temperature range and chamber-load thermal mass. Typical configurations use lab-grade recirculating chillers (e.g., -20 °C to +40 °C operating range) connected via insulated tubing.
Maintenance-free induction drive. No brush wear; same drive as the base Z600-S3.
Microprocessor-controlled speed regulation with 10-rpm pre-selection from 200 to 10,000 rpm. Running-time pre-selection in 10-sec increments to 99 h 59 min, plus continuous mode.
Imbalance switch-off. Same protection as the base SIEVA-3 — asymmetric loading or basket-load shift triggers automatic shutdown.
Automatic lid-lock with transparent lid. Visual monitoring of separation; lid cannot unlock during a run.
Stainless-steel chamber and housing. Chemical resistance for pharmaceutical / fine-chemical solvents; the chamber jacket is engineered for thermal exchange with the external loop.
Quick-key for short runs. Brief separations and clarity checks via single button.
Compatible with same basket and filter catalog as base SIEVA-3. All Z600-S3-* baskets and Z600-S3-F* filter pore sizes interchange between TC and non-TC chassis.
Frequently Asked Questions
How does the Z600-S3-TC differ from the base SIEVA-3? It adds a connection for an external temperature-equalization circulator, so chilled or heated fluid can be driven through the chamber jacket during separation.
Is the temperature circulator included? No — the external recirculating chiller/heater is customer-supplied. Hermle / Benchmark can recommend a compatible unit based on target temperature range and thermal load.
What is the maximum speed and RCF of the Z600-S3-TC? Same as the base SIEVA-3: 10,000 rpm / 7,825 × g with a 500 mL basket.
Are baskets and filters shared with the base Z600-S3? Yes — all Z600-S3 baskets and Z600-S3-F* filter pore sizes interchange between the TC and non-TC chassis.
What voltage does the Z600-S3-TC require? 120 V / 50–60 Hz standard; a 230 V / 50–60 Hz model is available by special order.
Ordering & Configuration
Ships configured per quote. The Z600-S3-TC body ships with operator's manual and 120 V power cord. The external temperature circulator is not included — order separately or supply from existing facility equipment. Hermle / Benchmark distributor can recommend compatible circulators based on target temperature range and thermal-load profile.
Compatible baskets and filters (shared catalog with Z600-S3):
- Z600-500-P — 500 mL perforated basket
- Z600-500-NP — 500 mL non-perforated basket
- Z600-S3-PC — SafeCoat 778-coated perforated basket
- Filter pore sizes: Z600-S3-F7u / -F20u / -F30u / -F50u, 10-filter packs
Variants in the SIEVA family:
- Z600-S3 — 120 V base SIEVA-3 (no temperature control)
This is a process-instrument purchase with workflow-dependent ancillary equipment (circulator selection, plumbing). Use the quote request to specify: workflow (target temperature range, thermal-load expectations, solvent compatibility, batch volume), basket configuration, filter pore-size packs, and whether circulator-sourcing recommendation is needed. Pre-installation site survey typical when a chilled circulator with significant cooling capacity is part of the install.
Warranty: 5-Year Hermle warranty (3 years full + 2 years drivetrain) on the SIEVA-3-TC chassis. The external circulator carries its own manufacturer warranty if sourced through Benchmark.
TC vs base SIEVA-3 selection: if your workflow runs at room temperature (~18–25 °C ambient lab temperature) and product stability isn't temperature-sensitive over a 5–60 minute filtration cycle, the base Z600-S3 is the right spec lower price point. The TC variant earns its premium when separation temperature must be held at a non-ambient set-point or controlled across multiple cycles.
