The Z366-06250-A50R is the 50 mL round-bottom tube adapter for the Hermle Z366-06250 6 × 250 mL angle rotor on the Z366 / Z366-K chassis — sold as a 2-pack. Each adapter holds 1 × 50 mL round-bottom tube; the 6-position rotor takes 3 packs (6 adapters) for full symmetric loading, delivering 6 × 50 mL round-bottom tubes per cycle (300 mL total) at the host rotor's high-RCF range (10,016 × g). Sister adapter to the A50 (50 mL Falcon conical) — same 50 mL volume but different tube envelope geometry.
Key Specifications
| SKU | Z366-06250-A50R |
| Type | Tube adapter — 250 mL angle position → 1 × 50 mL round-bottom |
| Pack quantity | 2 adapters per SKU (full 6-position rotor takes 3 units = 6 adapters) |
| Per-adapter capacity | 1 × 50 mL round-bottom tube |
| Per-cycle throughput (full configuration) | 6 × 50 mL round-bottom = 300 mL total per cycle |
| Tube format | 50 mL round-bottom glass or polypropylene (29 mm OD, 103 mm length) |
| Compatible host rotor | Z366-06250 (6 × 250 mL angle rotor) |
| Compatible chassis | Z366, Z366-K (refrigerated), and -E voltage variants |
| Max. operating speed (with adapter + tube) | Per Z366-06250 spec — 8,000 rpm at 10,016 × g maximum |
| Max. radius | 14 cm |
| Temperature at max speed (refrigerated chassis) | 3 °C |
| Angle | 28° (fixed-angle host rotor) |
| List price | $275 (2-pack) |
Compatibility & When to Order This SKU
Adapter pairing — Z366-06250 250 mL angle rotor only. Order this SKU when:
- Adding 50 mL round-bottom workflow to a Z366-06250 install — order 3 units for full 6-position symmetric loading.
- High-RCF cold-chain 50 mL round-bottom prep — when the workflow needs the >10,000 × g range with cold-chain integrity in 50 mL round-bottom format.
- Glass round-bottom 50 mL workflows — when the protocol requires glass for organic-solvent compatibility, repeated autoclave reuse, or precise volume measurement.
- Replacement adapters if a current set is damaged or worn.
Conical vs Round 50 mL — Why Two Adapter SKUs
The Z366-06250 50 mL adapter pair serves the same volume but different tube envelopes:
| Adapter | Tube format | Length |
| Z366-06250-A50 | 50 mL Falcon conical | 118 mm |
| Z366-06250-A50R (this SKU) | 50 mL round-bottom | 103 mm |
Match the adapter to the workflow's tube envelope. Using the wrong-envelope adapter risks tube fit problems and balance issues at the rotor's high RCF.
Application Profile
High-RCF cold-chain 50 mL round-bottom glass workflows — organic-extraction, chemical-prep, and precipitation workflows in 50 mL round-bottom glass at refrigerated temperature and >10,000 × g.
Glass-compatible cold-chain protein prep — TCA, ammonium-sulfate, organic-precipitation in 50 mL round-bottom glass on the refrigerated high-RCF chassis.
High-RCF cell-pellet recovery in 50 mL round-bottom — when cell-culture protocols specify round-bottom glass over conical for resuspension volume measurement or solvent-compatibility, with high-RCF tight pellet compaction.
Clinical and clinical-research 50 mL round-bottom workflows — when the workflow specifies round-bottom geometry over conical and the high-RCF cold-chain chassis is the appropriate platform.
Cross-format Z366-K core facilities — shared cores running both 50 mL conical (A50) and 50 mL round-bottom (this A50R) workflows on the same chassis benefit from stocking both adapter variants.
Mixed 250 / 50 mL round-bottom workflow consolidation — when the lab's primary chassis is the Z366-06250 for 250 mL bottle workflows and 50 mL round-bottom glass workflows are part of the protocol.
Ordering & Configuration
6-position symmetric loading. All 6 positions must use matching A50R adapters for symmetric balance at 8,000 rpm.
Adapter seat verification. Confirm each adapter is fully seated in its 250 mL position before loading the 50 mL round-bottom tube.
Tube cap confirmation. All 50 mL round-bottom tubes must be capped securely before spinning at 8,000 rpm.
Z366-06250-A50R ships as 2 adapters. 50 mL round-bottom tubes (glass or polypropylene) are operator-supplied.
Confirm at quote: host rotor (Z366-06250 in inventory), chassis pairing (Z366, Z366-K), tube format (50 mL round-bottom; conical uses A50), pack count (3 packs for full 6-position configuration), and lead time.
Warranty: 5-Year Hermle warranty (3 years full + 2 years drivetrain) on the adapters.
Z366-06250 50 mL adapter pair:
- Z366-06250-A50R (this product) — 50 mL round-bottom (103 mm length)
- Z366-06250-A50 — 50 mL Falcon conical (118 mm length)
Match the adapter to the workflow's tube envelope.
