3 × 50 mL Round Insert for Z446-04500 (2/pk)

The Z446-500-A50R is a 3-position 50 mL round-bottom tube insert for the Hermle Z446-04500 4 × 500 mL angle rotor on the Z446 / Z446-K chassis — sold as a 2-pack. Each insert holds 3 × 50 mL round-bottom tubes; the 4-position rotor takes 2 packs (4 inserts) for full symmetric loading, delivering 12 × 50 mL round-bottom tubes per cycle (600 mL total) at the host rotor's high-RCF range (10,367 × g). Higher per-cycle throughput than the Z446-500-A50 (1 × 50 mL conical, 4/cycle) — the A50R triples the 50 mL throughput by packing 3 tubes per insert.

Key Specifications

Compatibility & When to Order This SKU

Insert pairing — Z446-04500 500 mL angle rotor only. Order this SKU when:

1. Adding 50 mL round-bottom workflow to a Z446-04500 install — order 2 units for full 4-position symmetric loading (12 tubes/cycle, 600 mL total).
2. High-RCF cold-chain 50 mL round-bottom prep at higher throughput — when the workflow needs the >10,000 × g range with cold-chain integrity AND higher per-cycle throughput than the single-tube A50 insert delivers.
3. Glass round-bottom 50 mL workflows when the protocol requires glass for organic-solvent compatibility, repeated autoclave reuse, or precise volume measurement.
4. Replacement inserts if a current set is damaged or worn.

A50 vs A50R — Conical vs Round Trade-Off

The Z446-500 50 mL insert pair serves the same volume range but different tube formats and throughput levels:

The A50R triples per-cycle throughput (12 vs 4 tubes) but requires round-bottom tube format. The A50 is single-tube-per-position for conical Falcon-style tubes. Pick the A50R when the workflow uses round-bottom 50 mL tubes (glass or specialty formats) AND throughput matters; pick the A50 when conical Falcon tubes are the workflow standard.

Application Profile

High-RCF cold-chain 50 mL round-bottom prep at scale — patient sample fractionation, aliquot prep, biobank intake at 12 × 50 mL round-bottom per cycle on the cold-chain high-RCF rotor.

Cold-chain glass-compatible 50 mL workflows — organic-extraction, chemical-prep, and precipitation workflows in 50 mL round-bottom glass at refrigerated temperature and >10,000 × g, at higher per-cycle throughput.

High-RCF cell-pellet recovery in 50 mL round-bottom — when cell-culture protocols specify round-bottom over conical and the workflow benefits from 12 parallel preps per cycle.

Clinical and clinical-research 50 mL round-bottom workflows at scale — when the workflow specifies round-bottom geometry and the institutional throughput justifies the higher per-cycle batch size.

Density-gradient prep in 50 mL round-bottom at high RCF — Ficoll, Percoll, sucrose-gradient workflows requiring >10,000 × g in round-bottom format at scale.

Cross-format Z446-K core facilities — shared cores running both 50 mL round-bottom and 50 mL conical workflows benefit from stocking both A50R (round, 12/cycle) and A50 (conical, 4/cycle) variants.

Ordering & Configuration

4-position symmetric loading. All 4 positions on the host rotor must use matching A50R inserts for symmetric balance at 8,000 rpm.

Per-insert symmetric loading. Within each insert, the 3 round-bottom tubes should be balanced symmetrically — pair tubes by mass with the third position symmetric to the insert's central axis.

Tube cap confirmation. All 50 mL round-bottom tubes must be capped securely before spinning at 8,000 rpm.

Z446-500-A50R ships as 2 inserts. 50 mL round-bottom tubes (glass or polypropylene) are operator-supplied.

Confirm at quote: host rotor (Z446-04500 in inventory), chassis pairing (Z446 or Z446-K), tube format (50 mL round-bottom; conical uses A50), pack count (2 packs for full 4-position configuration = 12 tubes/cycle), and lead time.

Warranty: 5-Year Hermle warranty (3 years full + 2 years drivetrain) on the inserts.

Z446-500 50 mL insert pair (Z446-04500 4 × 500 mL angle rotor):

- Z446-500-A50R (this product) — 3 × 50 mL round-bottom (12/cycle, higher throughput)

- Z446-500-A50 — 1 × 50 mL Falcon conical (4/cycle, single-tube-per-insert)

Pick A50R for higher-throughput round-bottom workflow; pick A50 for single-tube-per-insert conical Falcon workflow.