The Z207-24SC is the 24-position spin column rotor for the Hermle Z207-M compact microcentrifuge, engineered for silica- and membrane-based spin column extraction kits (Qiagen, Zymo Research, Promega, Bio-Rad, NEB and equivalent kit chemistries). Spin columns combine a column body (filter membrane on a frit) with a 1.5 / 2.0 mL collection tube, and the column-plus-tube assembly is taller than a standard microtube alone. The SC rotor geometry accommodates this taller stack with the correct hub depth and spindle clearance. Z207-M only, engineered for the Z207-M chassis (not interchangeable with Z207-A or other Hermle families).
Key Specifications
| SKU | Z207-24SC |
| Type | Fixed-angle spin column rotor (24 position) |
| Capacity | 24 × 1.5 / 2.0 mL spin column kit assemblies |
| Compatible chassis | Z207-M only |
| Angle | 45° |
| Max. operating speed | 13,500 rpm |
| Max. RCF at operating speed | 15,484 × g |
| Max. radius | 7.6 cm (typical SC-rotor geometry) |
| Sample compatibility | Standard 1.5 / 2.0 mL spin column + collection tube assemblies (silica, anion-exchange, size-exclusion, affinity-bead column formats) |
| Adapter compatibility | C1008-A5-6 (0.5 mL); C1008-A2-6 (0.4/0.2 mL PCR): for downstream microtube use |
Compatibility & Configuration
Chassis compatibility: Z207-M only. The rotor body is engineered for the Z207-M compact-microcentrifuge spindle. Confirm chassis match at order.
Spin column kit compatibility: broad. Standard silica and membrane spin columns from major commercial extraction kits seat into the SC rotor positions:
- DNA extraction kits. Genomic DNA, plasmid mini-prep, gel extraction, PCR cleanup
- RNA extraction kits. Total RNA, mRNA, miRNA isolation
- Protein column kits. Affinity-tag purification at micro-prep scale, antibody cleanup, peptide enrichment
- Methylation, ChIP, ATAC-seq column kits. Epigenetic-prep workflows
The rotor geometry accepts standard column body dimensions (typical column OD ~9–11 mm; standard collection tube format 1.5 / 2.0 mL). Confirm at order if the workflow uses non-standard column dimensions (some specialty kits use proprietary geometries).
Why "SC" geometry matters. Standard microtube rotors (Z207-2420H, Z216-2420, etc.) are dimensioned for the microtube alone. Spin column assemblies stack the column body on top of the collection tube, increasing total height, the SC rotor's hub depth and spindle clearance accommodate this stack while maintaining the 45° angle and balanced rotation. Running spin columns in a non-SC microtube rotor is a fit problem (column may not seat fully) and a balance problem (irregular column-body weight distribution).
Application Profile
Routine DNA/RNA extraction at clinical-research and core-facility scale. The dominant use case. Most commercial extraction kits center on the silica spin-column workflow; the Z207-M + Z207-24SC combination delivers clean prep for downstream PCR, qPCR, sequencing, and microarray assays.
24-sample batches per cycle: matches the typical 96-well plate quadrant batch size (24 = 1/4 of a 96-well plate) common in extraction prep workflows.
Pre-PCR and pre-qPCR sample prep. Extract DNA/RNA into the SC rotor, then transfer eluate to PCR plate or strip for amplification.
Gel and PCR cleanup. Post-amplification or post-restriction-digest cleanup using gel-extraction or PCR-cleanup column kits at the bench-prep scale.
Plasmid mini-prep. Bacterial-culture-derived plasmid prep for cloning workflows; the SC rotor handles the typical 24-clone screening batch in a single cycle.
Protein affinity-prep at micro scale. His-tag, FLAG-tag, GST-tag affinity column kits at the analytical / pilot-prep scale where bench-format spin columns deliver sufficient yield.
Loading & Balance
24-position symmetric loading. Pair opposites (positions 1+13, 2+14, etc.) by mass. Spin column assemblies have variable mass during the workflow (column with binding buffer is heavier than column with eluate) so re-balance pairs at each spin step in a multi-step extraction protocol.
Column orientation. Spin columns must be oriented per the kit manufacturer's instructions, typically flow-through direction aligned with the rotor's outward radial axis. Most modern kits pre-orient the column body, but verify on first use of any new kit chemistry.
Selectable accel/decel. Z207-M chassis profiles apply; the unbraked extended-decel profile preserves loose silica-bound material during the elution step.
Ordering & Configuration
Z207-24SC ships as the rotor body alone. Spin column kits, reagents, and adapters for downstream microtube use (C1008-A5-6, C1008-A2-6) are sold separately or supplied per the user's chosen kit.
Confirm at quote: chassis pairing (Z207-M), kit chemistry intended (most major kits compatible; confirm if using non-standard column geometry), and lead time.
Warranty: 5-Year Hermle warranty (3 years full + 2 years drivetrain) on the rotor body.
Z207-M extraction-and-amplification rotor stack:
- Z207-24SC (this product): spin column extraction kit workflows (24 columns/cycle)
- Z207-2420H: hermetically sealed microtube rotor for biosafety microtube workflows
- Z207-3202: 4 × 8 PCR-strip rotor for downstream PCR after extraction
A common Z207-M setup pairs the 24SC with the 3202, extract DNA/RNA into the SC rotor, then run PCR setup or spin-down of PCR strips on the 3202 in the same chassis.
