The H3501 is the Incu-Shaker CO2 Mini — Benchmark Scientific's incubator-shaker with integrated CO2 atmosphere control at $11,399. NEW COMBINED PRODUCT FAMILY: combines the Incu-Shaker chassis (orbital shaking) with CO2 atmosphere control — enabling mammalian suspension cell culture workflows under controlled CO2 / pH conditions while shaking. Universal-input chassis (120 V or 230 V, 350 W).
Author confidence note (MEDIUM): No specific Incu-Shaker CO2 Mini brochure in available corpus. Confirm exact CO2 control range, sensor type, temperature range, RPM range, shaking orbit, and platform compatibility with Benchmark Scientific tech support. The combined CO2 + shaking workflow is a specialized niche — verify whether this chassis supports the same humidification / accessory ecosystem as the standalone myTemp CO2 Mini (H2300-HC2).
Voltage options: This unit can be ordered with European voltage requirements (230V/50Hz). Contact us to order.
Key Specifications
| SKU | H3501 |
| Type | Incubator-shaker with integrated CO2 atmosphere control |
| Voltage | 120 V or 230 V, 50–60 Hz (universal-input) |
| Power | 350 W |
| Includes | Non-slip rubber mat platform |
| Standalone CO2 incubator alternative | H2300-HC2 ($4,795 — no shaking) |
| Standalone Incu-Shaker alternative | H1001-M Mini ($3,635 — no CO2 control) |
| List price | $11,399 |
Why a CO2 + Shaking Combined Chassis
Mammalian suspension cell culture at production-relevant scale needs three simultaneous environmental conditions:
- Temperature control at 37 °C (incubator)
- CO2 atmosphere at ~5% for bicarbonate-buffered media pH stability
- Shaking / mixing for nutrient distribution and oxygen transfer
Standalone Incu-Shaker (H1001-M / H2010 family) covers (1) and (3) but lacks CO2 control — mammalian suspension culture media drift alkaline as CO2 escapes.
Standalone CO2 Incubator (H2300-HC2) covers (1) and (2) but lacks shaking — suspension culture cells settle and aggregate.
Combined Incu-Shaker CO2 Mini (this product) delivers all three simultaneously — the only Benchmark Scientific chassis that does so:
| Condition | Standalone Incu-Shaker (H1001-M) | Standalone CO2 Incubator (H2300-HC2) | H3501 Incu-Shaker CO2 Mini (this product) |
| Temperature 37 °C | ✓ | ✓ | ✓ |
| CO2 atmosphere control | — | ✓ | ✓ |
| Shaking / orbital mixing | ✓ | — | ✓ |
Pick the H3501 Incu-Shaker CO2 Mini when:
- Mammalian suspension cell culture at production-relevant scale (CHO cells, hybridoma, suspension HEK293)
- Bioreactor seed-train workflows at the shaking-flask scale before scale-up to true bioreactor
- Method-development workflows for suspension cell-culture optimization
- Antibody / protein production research at suspension-culture scale
Pick standalone alternatives if only one of the three conditions is required (significant cost savings):
- H1001-M Incu-Shaker Mini ($3,635) — saves $11,399.00 if no CO2 needed
- H2300-HC2 myTemp CO2 Mini ($4,795) — saves $6,604 if no shaking needed
Frequently Asked Questions
What does the H3501 combine? Temperature control (37 °C), CO2 atmosphere (~5%), and orbital shaking in one chassis — the only Benchmark Scientific unit that delivers all three simultaneously.
Why do suspension cultures need all three? Shaking keeps cells suspended and oxygenated, while CO2 control keeps bicarbonate-buffered media pH stable; a standalone shaker lacks CO2 and a standalone CO2 incubator lacks shaking.
What are the standalone alternatives? The H1001-M Incu-Shaker Mini ($3,635, no CO2) or the H2300-HC2 myTemp CO2 Mini ($4,795, no shaking).
What voltage and power does it use? 120 V or 230 V, 50–60 Hz, 350 W (universal input).
Ordering & Configuration
Procure CO2 gas regulator (H2300-REG, $423 — referenced in myTemp CO2 family) — likely required pairing for chassis CO2 inlet, but verify with Benchmark Scientific.
Plan CO2 cylinder source and tubing to bench location.
Confirm shaking format compatibility — non-slip rubber mat platform (vs full magnetic-clamp / spring-platform options). Verify whether H1000-MR / H1000-P platforms can replace the mat platform for flask workflows.
Confirm at quote: voltage / plug type, intended suspension cell-culture workflow, CO2 cylinder / regulator inclusion, platform compatibility, and lead time.
Warranty: Per Benchmark Scientific standard capital-equipment terms.
Incu-Shaker CO2 Mini family detail: The only Benchmark Scientific chassis combining temperature + CO2 + shaking in one footprint.
