The F1001 is the Accuris Smart-Q 100 Fluorometer — the mid-tier single-sample variant in the Accuris Smart-Q family. Per the brochure: sensitive quantification down to 0.1 pg/µL dsDNA, large color touch screen for programming and operation, built-in reagent calculators for sample preparation, and a compact 11 × 6 in. footprint. The Smart-Q 100 delivers Qubit-style fluorescence-based nucleic-acid quantification — higher specificity and accuracy than UV-absorbance methods (NanoDrop / SmartDrop UV-Vis) for low-concentration samples and for samples with purity issues. Sister to the F1008 Smart-Q 800 (8-channel parallel variant for higher throughput) and the F0100 Smart-Q Mini (entry-tier compact variant at lower cost).
Voltage options: This unit can be ordered with European voltage requirements (230V/50Hz). Contact us to order.
Key Specifications
| SKU | F1001 |
| Voltage | 115 V (North American outlet) |
| Type | Benchtop fluorometer — Smart-Q 100 (mid-tier single-sample) |
| Channels | Single-sample workflow |
| Sensitivity | Down to 0.1 pg/µL dsDNA |
| Display | Large color touch screen |
| Sample prep aids | Built-in reagent calculators for sample preparation |
| Footprint | 11 × 6 in. (compact, portable) |
| Detection chemistry | Fluorescence-based — Qubit-style dye-binding chemistry |
| Compatible kits | Accuris Fluorescent DNA / RNA / Protein Quantification Kits and assay tubes |
| List price | $4,385 |
Smart-Q Family Position
The Accuris Smart-Q fluorometer family ships in three tiers:
| Model | Channels | Position | Footprint | List price |
| F0100 Smart-Q Mini | Single-sample | Entry-tier compact | (Smaller) | $2,600 |
| F1001 Smart-Q 100 (this product) | Single-sample | Mid-tier full feature set | 11 × 6 in. | $4,385 |
| F1008 Smart-Q 800 | 8-channel parallel | Top-tier high-throughput | (Larger) | $7,230 |
The F1001 Smart-Q 100 is the right pick when:
- The lab needs routine fluorometric quantification with full feature set (touch screen, reagent calculators, data export)
- Single-sample workflow is sufficient (no need for the 8-channel parallel processing of the F1008)
- The full feature set justifies the price premium over the entry-tier F0100 Smart-Q Mini
Why Fluorescence Over UV-Absorbance
Fluorometric nucleic-acid quantification (Qubit-style, this instrument's chemistry) delivers higher specificity and accuracy than UV-absorbance methods for:
- Low-concentration samples — fluorescence detects dsDNA at 0.1 pg/µL, well below the UV-absorbance lower limit of detection
- Sample purity issues — fluorescence dye binds specifically to dsDNA (or specific RNA / protein targets), while UV-absorbance detects all dsDNA + ssDNA + RNA + protein + contaminants at the measurement wavelength
- Critical downstream applications — accurate quantification matters for NGS library prep success, qPCR setup, transfection efficiency, and similar workflows
For high-concentration samples where UV-absorbance is sufficient, the Accuris SmartDrop nano-spec family (NS1000, NS1010, NS1020) covers the workflow at lower per-sample reagent cost.
Application Profile
Per the F1001 brochure, the Smart-Q Fluorometers are particularly suited for workflows involving:
Next Generation Sequencing (NGS) — accurate library quantification before pooling and sequencing run normalization where Ct-equivalent low concentrations matter for run-quality outcomes.
PCR setup — accurate template quantification for low-input PCR setup and primer-template ratio optimization.
Transfection workflows — accurate plasmid concentration measurement for transfection-mix preparation and transfection-efficiency optimization.
Western blotting — accurate protein concentration measurement for SDS-PAGE loading normalization and Western blot signal-quantification consistency.
Immunoassays — accurate sample-concentration measurement for immunoassay loading volume calculation.
Mid-throughput single-sample workflows — labs that run routine fluorometric quantification on a per-sample basis (vs the 8-channel batch workflow that the F1008 delivers).
Frequently Asked Questions
What is the Smart-Q 100 (F1001)? The mid-tier single-sample fluorometer in the Accuris Smart-Q family, with a large color touchscreen and built-in reagent calculators.
How sensitive is the F1001? It quantifies down to 0.1 pg/µL dsDNA.
How does the F1001 fit within the Smart-Q family? Between the entry-tier F0100 Smart-Q Mini ($2,600, single-sample) and the top-tier F1008 Smart-Q 800 ($7,230, 8-channel parallel); the F1001 lists at $4,385.
Why choose fluorescence over UV-absorbance quantitation? Fluorescence dye binds specifically to dsDNA (or RNA/protein), detecting as low as 0.1 pg/µL and ignoring contaminants, whereas UV absorbance measures all species at the wavelength. For high-concentration samples, the SmartDrop nano-spec family (NS1000/NS1010/NS1020) is more cost-effective.
What kits does the F1001 use? Accuris Fluorescent DNA / RNA / Protein Quantification Kits and assay tubes.
Ordering & Configuration
Touch-screen interface. Large color touch screen for on-instrument workflow operation; sample-batch results stored on the instrument and exportable via standard data ports.
Built-in reagent calculators. The instrument's software calculates reagent volumes for sample prep — useful for workflows running the Accuris fluorescence kits where standard prep volumes are part of the protocol.
Compact portable footprint. 11 × 6 in. footprint fits in tight bench-space configurations; the instrument's portability supports multi-bench shared use.
Power configuration. 115 V (this SKU) for North American outlets; a 230 V variant is available by special order for UK / Europe / Australia outlets.
Confirm at quote: voltage configuration, accessory and consumables ecosystem alignment (Accuris Fluorescent Quantification Kits and assay tubes), training requirements, and lead time.
Warranty: Per Accuris Smart-Q family standard warranty terms — confirm at quote.
Smart-Q fluorometer family:
- F1001 (this product) — 230 V available by special order — Smart-Q 100 (mid-tier single-sample)
- F0100 (230 V by special order) — Smart-Q Mini (entry-tier compact)
- F1008 (230 V by special order) — Smart-Q 800 (8-channel parallel)
Pick the F1001 Smart-Q 100 for mid-tier single-sample fluorometric quantification with the full Smart-Q feature set.
