The F1001 is the Accuris Smart-Q 100 Fluorometer, the mid-tier single-sample variant in the Accuris Smart-Q family. Per the brochure: sensitive quantification down to 0.1 pg/µL dsDNA, large color touch screen for programming and operation, built-in reagent calculators for sample preparation, and a compact 11 × 6 in. footprint. The Smart-Q 100 delivers Qubit-style fluorescence-based nucleic-acid quantification, higher specificity and accuracy than UV-absorbance methods (NanoDrop / SmartDrop UV-Vis) for low-concentration samples and for samples with purity issues. Sister to the F1008 Smart-Q 800 (8-channel parallel variant for higher throughput) and the F0100 Smart-Q Mini (entry-tier compact variant at lower cost).
Voltage options: This unit can be ordered with European voltage requirements (230V/50Hz). Contact us to order.
Key Specifications
| SKU | F1001 |
| Voltage | 115 V (North American outlet) |
| Type | Benchtop fluorometer: Smart-Q 100 (mid-tier single-sample) |
| Channels | Single-sample workflow |
| Sensitivity | Down to 0.1 pg/µL dsDNA |
| Display | Large color touch screen |
| Sample prep aids | Built-in reagent calculators for sample preparation |
| Footprint | 11 × 6 in. (compact, portable) |
| Detection chemistry | Fluorescence-based / Qubit-style dye-binding chemistry |
| Compatible kits | Accuris Fluorescent DNA / RNA / Protein Quantification Kits and assay tubes |
| List price | $4,385 |
Smart-Q Family Position
The Accuris Smart-Q fluorometer family ships in three tiers:
| Model | Channels | Position | Footprint | List price |
| F0100 Smart-Q Mini | Single-sample | Entry-tier compact | (Smaller) | $2,600 |
| F1001 Smart-Q 100 (this product) | Single-sample | Mid-tier full feature set | 11 × 6 in. | $4,385 |
| F1008 Smart-Q 800 | 8-channel parallel | Top-tier high-throughput | (Larger) | $7,230 |
The F1001 Smart-Q 100 is the right pick when:
- The lab needs routine fluorometric quantification with full feature set (touch screen, reagent calculators, data export)
- Single-sample workflow is sufficient (no need for the 8-channel parallel processing of the F1008)
- The full feature set justifies the price premium over the entry-tier F0100 Smart-Q Mini
Why Fluorescence Over UV-Absorbance
Fluorometric nucleic-acid quantification (Qubit-style, this instrument's chemistry) delivers higher specificity and accuracy than UV-absorbance methods for:
- Low-concentration samples. Fluorescence detects dsDNA at 0.1 pg/µL, well below the UV-absorbance lower limit of detection
- Sample purity issues. Fluorescence dye binds specifically to dsDNA (or specific RNA / protein targets), while UV-absorbance detects all dsDNA + ssDNA + RNA + protein + contaminants at the measurement wavelength
- Critical downstream applications. Accurate quantification matters for NGS library prep success, qPCR setup, transfection efficiency, and similar workflows
For high-concentration samples where UV-absorbance is sufficient, the Accuris SmartDrop nano-spec family (NS1000, NS1010, NS1020) covers the workflow at lower per-sample reagent cost.
Application Profile
Per the F1001 brochure, the Smart-Q Fluorometers are particularly suited for workflows involving:
Next Generation Sequencing (NGS). Accurate library quantification before pooling and sequencing run normalization where Ct-equivalent low concentrations matter for run-quality outcomes.
PCR setup. Accurate template quantification for low-input PCR setup and primer-template ratio optimization.
Transfection workflows. Accurate plasmid concentration measurement for transfection-mix preparation and transfection-efficiency optimization.
Western blotting. Accurate protein concentration measurement for SDS-PAGE loading normalization and Western blot signal-quantification consistency.
Immunoassays. Accurate sample-concentration measurement for immunoassay loading volume calculation.
Mid-throughput single-sample workflows. Labs that run routine fluorometric quantification on a per-sample basis (vs the 8-channel batch workflow that the F1008 delivers).
Frequently Asked Questions
What is the Smart-Q 100 (F1001)? The mid-tier single-sample fluorometer in the Accuris Smart-Q family, with a large color touchscreen and built-in reagent calculators.
How sensitive is the F1001? It quantifies down to 0.1 pg/µL dsDNA.
How does the F1001 fit within the Smart-Q family? Between the entry-tier F0100 Smart-Q Mini ($2,600, single-sample) and the top-tier F1008 Smart-Q 800 ($7,230, 8-channel parallel); the F1001 lists at $4,385.
Why choose fluorescence over UV-absorbance quantitation? Fluorescence dye binds specifically to dsDNA (or RNA/protein), detecting as low as 0.1 pg/µL and ignoring contaminants, whereas UV absorbance measures all species at the wavelength. For high-concentration samples, the SmartDrop nano-spec family (NS1000/NS1010/NS1020) is more cost-effective.
What kits does the F1001 use? Accuris Fluorescent DNA / RNA / Protein Quantification Kits and assay tubes.
Ordering & Configuration
Touch-screen interface. Large color touch screen for on-instrument workflow operation; sample-batch results stored on the instrument and exportable via standard data ports.
Built-in reagent calculators. The instrument's software calculates reagent volumes for sample prep, useful for workflows running the Accuris fluorescence kits where standard prep volumes are part of the protocol.
Compact portable footprint. 11 × 6 in. footprint fits in tight bench-space configurations; the instrument's portability supports multi-bench shared use.
Power configuration. 115 V (this SKU) for North American outlets; a 230 V variant is available by special order for UK / Europe / Australia outlets.
Confirm at quote: voltage configuration, accessory and consumables ecosystem alignment (Accuris Fluorescent Quantification Kits and assay tubes), training requirements, and lead time.
Warranty: Per Accuris Smart-Q family standard warranty terms. Confirm at quote.
Smart-Q fluorometer family:
- F1001 (this product): 230 V available by special order, Smart-Q 100 (mid-tier single-sample)
- F0100 (230 V by special order): Smart-Q Mini (entry-tier compact)
- F1008 (230 V by special order): Smart-Q 800 (8-channel parallel)
Pick the F1001 Smart-Q 100 for mid-tier single-sample fluorometric quantification with the full Smart-Q feature set.
